For the first clip , scientists have mark distinct differences between the head and gene expression of military man and women with austere depression , suggesting that doctors should appear at the possibility of sexual practice - specific treatments for certain genial health problems .

The enquiry , issue this week in the journalBiological Psychiatry , identify that world and women with   major   depressive disorder ( MDD ) in reality have paired variety in the expression of 52 separate genes . While women had increase expression of genes affecting synapse function , men had fall expression of the same cistron . Equally , cleaning woman had decreased expression of factor involve the immune system , yet men experience the opposition .

In a post - mortem procedure , the researchers dissect the brains of 50 people with major depressive disorder ( 26 human race and 24 women ) and compare them to the same number of unaffected brains . They focused on analyzing the three master learning ability region that help regulate humour   – the prior cingulate cortex , dorsolateral prefrontal cortex , and corpus amygdaloideum   – and that are nonadaptive in people with severe depressive disorders .

" While researchers have been examining the brain of downcast subjects for decades , many of these subject field included only mankind , " pronounce lead author Dr Marianne Seney from the University of Pittsburgh .

It ’s worth think of that major depressive disorder affects women roughly twice as often as man and that women are three metre as likely to have irregular clinical depression . While this could be linked to a whole crowd of societal , cultural , orenvironmental factor , this study also evoke there could be a molecular factor feign the way clinical depression manifests itself . Of naturally , the subjects were deadened , so it was not possible for the researchers to see how these changes in gene manifestation affected them in person . Nevertheless , it certainly hints at the   ideathat   sex - specific treatments could be a new avenue for research worker to research .

" For example , our result suggest that treatments to inhibit immune function might be more appropriate for men with MDD , while treatment which boost immune function might be more appropriate for women with MDD , " the study explains . " Alternatively , succeeding treatments might point to aim the limited shared pathology present in both man and women with MDD . "